Predictive significance of preoperative serum VEGF-C and VEGF-D, independently and combined with Ca19-9, for the presence of malignancy and lymph node metastasis in patients with gastric cancer.

@article{Tsirlis2010PredictiveSO,
  title={Predictive significance of preoperative serum VEGF-C and VEGF-D, independently and combined with Ca19-9, for the presence of malignancy and lymph node metastasis in patients with gastric cancer.},
  author={Theodoros D Tsirlis and Alkiviadis I. Kostakis and George I Papastratis and Kiriaki Masselou and Ioannis N. Vlachos and Antonios Papachristodoulou and Nikolaos I Nikiteas},
  journal={Journal of surgical oncology},
  year={2010},
  volume={102 6},
  pages={699-703}
}
BACKGROUND Cumulative evidence demonstrate that lymphangiogenic vascular endothelial growth factors (VEGF)-C and -D are over-expressed and associated to lymph node metastasis (LNM) in gastric cancer. The aim of this study is to investigate whether preoperative serum levels of VEGF-C and VEGF-D could be useful tumor markers in patients with operable gastric adenocarcinoma. METHODS We prospectively examined serum samples from 40 patients and 40 non-cancer controls using enzyme-linked… CONTINUE READING

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Serum levels of vascular endothelial growth factor in gastric cancer patients.

Journal of surgical oncology • 2011
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