Predictive properties of serum-prostate-specific antigen testing in a community-based setting.

@article{Jacobsen1996PredictivePO,
  title={Predictive properties of serum-prostate-specific antigen testing in a community-based setting.},
  author={Steven J. Jacobsen and Erik J. Bergstralh and Harry A. Guess and Slavica K. Katusic and George G. Klee and Joseph E. Oesterling and Michael M. Lieber},
  journal={Archives of internal medicine},
  year={1996},
  volume={156 21},
  pages={2462-8}
}
BACKGROUND Most studies that have described the sensitivity and specificity of prostate-specific antigen (PSA) as a screening test have been conducted in urology practice settings or in media-based screening programs. The control patients from these settings may have a higher prevalence of urologic disorders that increase serum PSA levels than that of the general population in which screening efforts might take place, leading to biased estimates of sensitivity and specificity. OBJECTIVE To… CONTINUE READING