Predictive population dose-response assessment for Cryptosporidium parvum: infection endpoint.

@article{Englehardt2004PredictivePD,
  title={Predictive population dose-response assessment for Cryptosporidium parvum: infection endpoint.},
  author={James D. Englehardt and Jeff Swartout},
  journal={Journal of toxicology and environmental health. Part A},
  year={2004},
  volume={67 8-10},
  pages={651-66}
}
Data validation of safe doses of pathogens in drinking water consistent with public health goals is not possible due to the number of subjects that would be needed at each dose. Because of this problem, together with the difficulty in extrapolating pathogenic response between species, and the ability of microbes to adapt rapidly, confidence-level-dependent assessments of Cryptosporidium parvum dose-response have been developed. However, these results, even on a relative basis, are dependent on… CONTINUE READING

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