Predictive parameters for granulocyte colony-stimulating factor-induced peripheral blood stem cell mobilization.

@article{Okano2008PredictivePF,
  title={Predictive parameters for granulocyte colony-stimulating factor-induced peripheral blood stem cell mobilization.},
  author={Akira Okano and Eishi Ashihara and Chihiro Shimazaki and Hitoji Uchiyama and Tohru Inaba and Kyoko Taniguchi and Taira Maekawa and Masafumi Taniwaki},
  journal={Journal of clinical apheresis},
  year={2008},
  volume={23 6},
  pages={
          171-7
        }
}
To improve the selection of donors for allogeneic stem cell transplantation, it is important to identify reliable parameters that predict CD34+-cell yields after granulocyte-colony stimulating factor (G-CSF)-induced peripheral blood stem cell (PBSC) mobilization. We retrospectively investigated the peripheral blood (PB) kinetics of white blood cells (WBCs), CD34+ cells, matrix metalloproteinases (MMP)-9 and -2, and tissue inhibitors of metalloproteinases (TIMP)-1 and -2 in 15 healthy donors… CONTINUE READING