Predictive models of subcellular localization of long RNAs.

  title={Predictive models of subcellular localization of long RNAs.},
  author={Binyamin Zuckerman and Igor Ulitsky},
  volume={25 5},
Export to the cytoplasm is a key regulatory junction for both protein-coding mRNAs and long noncoding RNAs (lncRNAs), and cytoplasmic enrichment varies dramatically both within and between those groups. We used a new computational approach and RNA-seq data from human and mouse cells to quantify the genome-wide association between cytoplasmic/nuclear ratios of both gene groups and various factors, including expression levels, splicing efficiency, gene architecture, chromatin marks, and sequence… CONTINUE READING
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