Predictive factors of bleeding and thrombosis during induction therapy in acute promyelocytic leukemia-a single center experience in 34 patients.

@article{Dally2005PredictiveFO,
  title={Predictive factors of bleeding and thrombosis during induction therapy in acute promyelocytic leukemia-a single center experience in 34 patients.},
  author={Najib Dally and R. H. Hoffman and Nuhad Haddad and Galit Sarig and Jacob M. Rowe and Benjamin Brenner},
  journal={Thrombosis research},
  year={2005},
  volume={116 2},
  pages={109-14}
}
In this retrospective study, the hemorrhagic and thrombotic events are reported at presentation and during induction in 34 consecutive acute promyelocytic leukemia (APL) patients treated in a single referral center. The most consistent hemostatic abnormality was decreased fibrinogen level (<150 mg/dL) found in 21 patients (61%), partial thromboplastin time (PTT) was normal almost in all patients. A mildly prolonged prothrombin time (PT) was observed in 14 patients (44%). Median platelet count… CONTINUE READING
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