Predictive environmental risk assessment of chemical mixtures: a conceptual framework.

@article{Backhaus2012PredictiveER,
  title={Predictive environmental risk assessment of chemical mixtures: a conceptual framework.},
  author={Thomas Backhaus and M. S. John B. Faust},
  journal={Environmental science & technology},
  year={2012},
  volume={46 5},
  pages={2564-73}
}
Environmental risks of chemicals are still often assessed substance-by-substance, neglecting mixture effects. This may result in risk underestimations, as the typical exposure is toward multicomponent chemical "cocktails". We use the two well established mixture toxicity concepts (Concentration Addition (CA) and Independent Action (IA)) for providing a tiered outline for environmental hazard and risk assessments of mixtures, focusing on general industrial chemicals and assuming that the "base… CONTINUE READING
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