Predictive biomarkers for personalised anti-cancer drug use: discovery to clinical implementation.

@article{Alymani2010PredictiveBF,
  title={Predictive biomarkers for personalised anti-cancer drug use: discovery to clinical implementation.},
  author={Nayef A Alymani and Murray D. Smith and David J. Williams and Russell David Petty},
  journal={European journal of cancer},
  year={2010},
  volume={46 5},
  pages={869-79}
}
A priority translational research objective in cancer medicine is the discovery of novel therapeutic targets for solid tumours. Ideally, co-discovery of predictive biomarkers occurs in parallel to facilitate clinical development of agents and ultimately personalise clinical use. However, the identification of clinically useful predictive biomarkers for solid tumours has proven challenging with many initially promising biomarkers failing to translate into clinically useful applications. In… CONTINUE READING
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Biomarkers for therapeutic efficacy

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Highly Influential
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