Corpus ID: 212543688

Predictive Value of PKM2 Expression in Advanced Non-Small Cell Lung Cancer Patients (NSCLC) Treated with First line Platinum-based Chemotherapy

@inproceedings{Sheta2017PredictiveVO,
  title={Predictive Value of PKM2 Expression in Advanced Non-Small Cell Lung Cancer Patients (NSCLC) Treated with First line Platinum-based Chemotherapy},
  author={Mohamed A Sheta and Omnia Abd el-fattah and Hanan Al-Saeid Al-Shenawy},
  year={2017}
}
Background: The aim of the study was, to assess the expression of pyruvate kinase isoform M2 (PKM2) in advanced NSCLC patients treated with first line platinum-based chemotherapy and evaluate its predictive value on both progression free survival (PFS) and overall survival (OS). Methods: 72 cases with h istologically confirmed stage IIIB and IV NSCLC who were treated with front-line platinum-based chemotherapy. Th irty two NSCLC patients were treated with first line non-platinum-based doublets… CONTINUE READING

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