Predictive Value of Early Tumor Shrinkage and Density Reduction of Lung Metastases in Patients With Metastatic Colorectal Cancer Treated With Regorafenib.

@article{Vanwynsberghe2017PredictiveVO,
  title={Predictive Value of Early Tumor Shrinkage and Density Reduction of Lung Metastases in Patients With Metastatic Colorectal Cancer Treated With Regorafenib.},
  author={Hannes Vanwynsberghe and Xander Verbeke and Johan Coolen and Eric Van Cutsem},
  journal={Clinical colorectal cancer},
  year={2017},
  volume={16 4},
  pages={
          377-380
        }
}
INTRODUCTION The benefit of regorafenib in colorectal cancer is not very pronounced. At present, there is lack of predictive biological or radiological markers. We studied if density reduction or small changes in size of lung metastases could be a predictive marker. METHODS We retrospectively measured density in size of lung metastases of all patients included in the CORRECT and CONSIGN trials at our center. Contrast-enhanced CT scan at baseline and at week 8 were compared. Data of… CONTINUE READING
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