Predictive Factors for Postherpetic Neuralgia Using Ordered Logistic Regression Analysis

  title={Predictive Factors for Postherpetic Neuralgia Using Ordered Logistic Regression Analysis},
  author={Yuko Kanbayashi and Keiko Onishi and Keita Fukazawa and Kousuke Okamoto and Hiroshi Ueno and Tatsuya Takagi and Toyoshi Hosokawa},
  journal={The Clinical Journal oF Pain},
Objectives:To identify predictive factors for the occurrence of postherpetic neuralgia (PHN). Methods:The participants were 73 herpes zoster patients who had been treated at the pain clinic of our hospital between January 2008 and June 2010. Variables present at the initial visit were extracted from the clinical records for regression analysis of factors related to the occurrence of PHN. The following scores for response were used: 0=no PHN after 3 months; 1=PHN present after 3 months but… 
Predictive factors for postherpetic neuralgia.
The result of this study may not be generalizable to patients with herpes zoster who consult their primary care physician, as the included patients were recruited from a pain clinic and their mean initial pain VAS score amounted 64.6, which is significantly higher than the mean score in a general practice-based trial.
Predictive Factors for Postherpetic Neuralgia and Recent Pharmacotherapies
Predictive Factors for Postherpetic Neuralgia Using Ordered Logistic Regression Analysis is reported on the premise that statistical identifica‐ tion of significant predictors for PHN would contribute to the establishment of an evidencebased medicine approach to the optimal treatment of PHN.
A systematic review and meta-analysis of risk factors for postherpetic neuralgia
A number of clinical features of acute zoster are risk factors for postherpetic neuralgia, yet aside from age-associated risks, evidence regarding risk factors to inform zoster vaccination policy is currently limited.
Efficacy of continuous epidural block in acute herpes zoster
Investigation of efficacy of continuous epidural block for prevent postherpetic neuralgia progression in cases of acute herpes zoster with severe pain and also to identify predictive factors for PHN in such conditions found advanced age and severe initial pain intensity were predictive factors of PHN development.
Predictors of postherpetic neuralgia in patients with herpes zoster: a pooled analysis of prospective cohort studies from North and Latin America and Asia.
  • K. Kawai, E. Rampakakis, C. Acosta
  • Medicine
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
  • 2015
The Epidemiology of Herpes Zoster and Postherpetic Neuralgia in China: Results from a Cross-Sectional Study
Estimates of the prevalence of herpes zoster and postherpetic neuralgia in the general adult population in urban China are similar to previously reported rates in China and worldwide, and highlight the global nature of HZ and PHN.
Understanding risk factors for herpes zoster and postherpetic neuralgia in UK primary care: investigations to inform vaccine policy.
Low antiviral use at zoster diagnosis suggests treatment guidelines be revised to encourage greater use, especially among the immunosuppressed and older individuals who are recommended, but not routinely given, antivirals.
Peptic ulcer as a risk factor for postherpetic neuralgia in adult patients with herpes zoster
It is found that 60 years of age and older, peptic ulcer and greater acute herpetic pain are independent predictors for postherpetic neuralgia in adult herpes zoster patients.
Quantification of risk factors for herpes zoster: population based case-control study
A range of conditions were associated with increased risk of zoster and the increased risk was proportionally greater in younger age groups, highlighting the need for alternative risk reduction strategies in these groups.


Predictors of postherpetic neuralgia among patients with herpes zoster: a prospective study.
Risk factors for postherpetic neuralgia in patients with herpes zoster
The independent contributions to the prediction of PHN made by older age, female sex, presence of a prodrome, greater rash severity, and greater acute pain severity suggest that these risk factors reflect different mechanisms that each contribute to the development ofPHN.
A study of shingles and the development of postherpetic neuralgia in East London
Treatment of acute shingles in this observational community‐based study was suboptimal in 50% of cases and more accurate prediction of which subset of elderly patients are most at risk of PHN may enable targeted prescribing of the most potent drugs to those most likely to benefit.
Clinical and psychosocial correlates of post‐herpetic neuralgia
In a univariate analysis, post‐herpetic neuralgia was associated significantly with older age, longer duration of prodromal pain, greater acute pain intensity, greater extent of rash, presence of abnormal sensations and use of systemic antiviral therapy.
Clinical Correlates of Prolonged Pain in Japanese Patients with Acute Herpes Zoster
It is suggested that advanced age, the presence of clustered vesicles, and disturbed sleep and hypaesthesia influence the prolongation of herpes zoster pain.
Antiviral treatment for preventing postherpetic neuralgia.
There is insufficient evidence from randomised controlled trials to determine whether other antiviral treatments prevent PHN, and additional well-designed, randomisedcontrolled trials of famciclovir or other new antiviral agents, with a greater number of participants are needed.
Epidemiology and Impact on Quality of Life of Postherpetic Neuralgia and Painful Diabetic Neuropathy
  • K. Schmader
  • Medicine, Psychology
    The Clinical journal of pain
  • 2002
Both conditions are common complications of their underlying disorders and can profoundly diminish the quality of life of affected persons.
Acute pain in herpes zoster: the famciclovir database project