Prediction of treatment outcome in patients with chronic hepatitis C: Significance of baseline parameters and viral dynamics during therapy

@inproceedings{Berg2003PredictionOT,
  title={Prediction of treatment outcome in patients with chronic hepatitis C: Significance of baseline parameters and viral dynamics during therapy},
  author={Thomas Berg and Christoph Sarrazin and Eva Herrmann and Holger Hinrichsen and Tilman J Gerlach and Reinhart Zachoval and Bertram Wiedenmann and Uwe Hopf and Stefan Zeuzem},
  year={2003}
}
In patients with chronic hepatitis C virus (HCV) infection scheduled for a 48-week treatment period, premature discontinuation of treatment was previously recommended if HCV-RNA levels remained detectable at week 24 of therapy. Considering the number of side effects and treatment costs, measurement of initial viral decline during therapy may identify virologic nonresponse earlier than 24 weeks. We retrospectively analyzed 260 European patients treated with standard or pegylated interferon alfa… CONTINUE READING

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