Prediction of the excessive perioperative bleeding in patients undergoing coronary artery bypass grafting: role of aspirin and platelet glycoprotein IIIa polymorphism.

@article{Morawski2005PredictionOT,
  title={Prediction of the excessive perioperative bleeding in patients undergoing coronary artery bypass grafting: role of aspirin and platelet glycoprotein IIIa polymorphism.},
  author={Włodzimierz Morawski and Marek Sanak and Marek Cisowski and Michał Szczeklik and Wojciech Szczeklik and Jerzy Dropiński and T Waclawczyk and Rafal Ulczok and Andrzej A. Bochenek},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2005},
  volume={130 3},
  pages={791-6}
}
OBJECTIVE The presence of the glycoprotein IIIa allele PlA2 is associated with enhanced thrombin formation and an impaired antithrombotic action of aspirin, which could favor coronary thrombosis. We wondered whether PlA1/A2 genetic polymorphism could affect the postoperative bleeding in patients undergoing coronary artery bypass grafting. We also aimed to… CONTINUE READING