Prediction of the Number of Residue Contacts in Proteins

  title={Prediction of the Number of Residue Contacts in Proteins},
  author={Piero Fariselli and Rita Casadio},
  journal={Proceedings. International Conference on Intelligent Systems for Molecular Biology},
Knowing the number of residue contacts in a protein is crucial for deriving constraints useful in modeling protein folding and/or scoring remote homology search. Here we focus on the prediction of residue contacts and show that this figure can be predicted with a neural network based method. The accuracy of the prediction is 12 percentage points higher than that of a simple statistical method. The neural network is used to discriminate between two different states of residue contacts… CONTINUE READING