Prediction of signaling networks by information propagation on protein-protein interaction networks integrated with GO annotations

Abstract

The experimental study of signal transduction over a decade has made a substantial contribution to understanding functional mechanisms in a cell. A signaling pathway represents a linear path of a signaling cascade involving a series of proteins. As an advanced model, multiple linear pathways with extensive cross-talk between receptors can be merged into a… (More)
DOI: 10.1109/BIBM.2013.6732475

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