Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer.

  title={Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer.},
  author={T. Nakao and T. Iwata and Masanori Hotchi and K. Yoshikawa and J. Higashijima and M. Nishi and C. Takasu and S. Eto and Hiroki Teraoku and M. Shimada},
  journal={Oncology reports},
  volume={34 4},
  • T. Nakao, T. Iwata, +7 authors M. Shimada
  • Published 2015
  • Medicine
  • Oncology reports
  • Preoperative chemoradiotherapy (CRT) has become the standard treatment for patients with locally advanced rectal cancer. However, no specific biomarker has been identified to predict a response to preoperative CRT. The aim of the present study was to assess the gene expression patterns of patients with advanced rectal cancer to predict their responses to preoperative CRT. Fifty-nine rectal cancer patients were subjected to preoperative CRT. Patients were randomly assigned to receive CRT with… CONTINUE READING
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