Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer.

@article{Nakao2015PredictionOR,
  title={Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer.},
  author={Toshihiro Nakao and Takashi Iwata and Masanori Hotchi and Kozo Yoshikawa and Jun Higashijima and Masaaki Nishi and Chie Takasu and Shohei Eto and Hiroki Teraoku and Mitsuo Shimada},
  journal={Oncology reports},
  year={2015},
  volume={34 4},
  pages={
          1961-7
        }
}
Preoperative chemoradiotherapy (CRT) has become the standard treatment for patients with locally advanced rectal cancer. However, no specific biomarker has been identified to predict a response to preoperative CRT. The aim of the present study was to assess the gene expression patterns of patients with advanced rectal cancer to predict their responses to preoperative CRT. Fifty-nine rectal cancer patients were subjected to preoperative CRT. Patients were randomly assigned to receive CRT with… Expand
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