Prediction of relapse with the TRH test and prophylactic amitriptyline in 39 patients with endogenous depression.

@article{KrogMeyer1984PredictionOR,
  title={Prediction of relapse with the TRH test and prophylactic amitriptyline in 39 patients with endogenous depression.},
  author={I Krog-Meyer and Christian Kirkegaard and B Kijne and B I Lumholtz and Eric Smith and L Lykke-Olesen and N. Bj\orum},
  journal={The American journal of psychiatry},
  year={1984},
  volume={141 8},
  pages={945-8}
}
The authors conducted a double-blind prospective study of 39 patients with unipolar endogenous depression who recovered after ECT. Thyrotropin (TSH)-releasing hormone (TRH) tests were performed before and after ECT. Patients were divided into three groups on the basis of their altered TSH response: Persistent remission was predicted for patients in group 1 (N = 15) and relapse was predicted for groups 2A (N = 13) and 2B (N = 11). Patients in groups 1 and 2A received placebo and those in group… CONTINUE READING
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