Prediction of relapse by day 100 BCR-ABL quantification after allogeneic stem cell transplantation for chronic myeloid leukemia

@article{Asnafi2006PredictionOR,
  title={Prediction of relapse by day 100 BCR-ABL quantification after allogeneic stem cell transplantation for chronic myeloid leukemia},
  author={Vahid Asnafi and M. Teresa Cuesta Rubio and Eric C M Delabesse and Esther Villar and Frederic Davi and Ghandi Damaj and Isabelle Hirsch and Nathalie Dh{\'e}din and J. P. Vernant and B. Varet and Agn{\'e}s Buzyn and Elizabeth A Macintyre},
  journal={Leukemia},
  year={2006},
  volume={20},
  pages={793-799}
}
Chronic myeloid leukemia (CML) relapse after allogeneic stem cell transplantation (SCT) is a relatively frequent situation, which is correlated to disease status, time from diagnosis to transplant and T-cell depletion. We evaluated the potential for early minimal residual disease (MRD) BCR-ABL quantification to predict relapse of CML patients receiving allogeneic SCT. Minimal residual disease was analyzed by real-time quantitative reverse transcriptase-polymerase chain reaction (RQ-PCR) at day… CONTINUE READING
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