Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America.

@article{Cannon2008PredictionOP,
  title={Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America.},
  author={Tyrone D. Cannon and Kristin S. Cadenhead and Barbara A. Cornblatt and Scott W. Woods and Jean Addington and Elaine Walker and Larry J. Seidman and Diana Perkins and Ming T. Tsuang and Thomas H. McGlashan and Robert K Heinssen},
  journal={Archives of general psychiatry},
  year={2008},
  volume={65 1},
  pages={28-37}
}
CONTEXT Early detection and prospective evaluation of individuals who will develop schizophrenia or other psychotic disorders are critical to efforts to isolate mechanisms underlying psychosis onset and to the testing of preventive interventions, but existing risk prediction approaches have achieved only modest predictive accuracy. OBJECTIVES To determine the risk of conversion to psychosis and to evaluate a set of prediction algorithms maximizing positive predictive power in a clinical high… CONTINUE READING
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