Prediction of patient responses to antihypertensive drugs using genetic polymorphisms: investigation of renin-angiotensin system genes.

Abstract

OBJECTIVE To investigate whether the M235T polymorphism of the angiotensinogen (AGT) gene and the insertion/deletion (I/D) polymorphism of the angiotensin-1 converting enzyme (ACE) gene predict blood pressure response to different antihypertensive agents. DESIGN Sixty-three patients with untreated essential hypertension were randomly assigned in a placebo… (More)

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@article{Dudley1996PredictionOP, title={Prediction of patient responses to antihypertensive drugs using genetic polymorphisms: investigation of renin-angiotensin system genes.}, author={Christopher Dudley and Bernard D Keavney and Barbara Casadei and Joe Conway and Robert J Bird and Peter J Ratcliffe}, journal={Journal of hypertension}, year={1996}, volume={14 2}, pages={259-62} }