Prediction of operator-binding protein by discriminant analysis.

  title={Prediction of operator-binding protein by discriminant analysis.},
  author={Kazuhide Nakata and Jacob V. Maizel},
  journal={Gene analysis techniques},
  volume={6 6},
A number of operator-binding proteins contain similar sequence features to Cro and cI repressors of bacteriophage and CAP protein of Escherichia coli, such as conserved amino acids at constant positions. However, these sequence patterns also occur in proteins that are not operator-binding. We use sequence analogy information in conjunction with a pattern recognition algorithm. The functional and structural properties, e.g., distributions of hydrophobicity, hydrophilicity, charged amino acids… CONTINUE READING

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