Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.

@article{Kotronen2009PredictionON,
  title={Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.},
  author={Anna Kotronen and Markku Peltonen and Antti Hakkarainen and Ksenia Sevastianova and Robert Bergholm and Lina M. Johansson and Nina Lundbom and Aila M. Rissanen and Martin Ridderstr{\aa}le and Leif Groop and Marju Orho-Melander and Hannele Yki-J{\"a}rvinen},
  journal={Gastroenterology},
  year={2009},
  volume={137 3},
  pages={865-72}
}
BACKGROUND & AIMS Our aims were to develop a method to accurately predict non-alcoholic fatty liver disease (NAFLD) and liver fat content based on routinely available clinical and laboratory data and to test whether knowledge of the recently discovered genetic variant in the PNPLA3 gene (rs738409) increases accuracy of the prediction. METHODS Liver fat content was measured using proton magnetic resonance spectroscopy in 470 subjects, who were randomly divided into estimation (two thirds of… CONTINUE READING
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