Prediction of neuropeptide prohormone cleavages with application to RFamides.

@article{Southey2006PredictionON,
  title={Prediction of neuropeptide prohormone cleavages with application to RFamides.},
  author={Bruce R. Southey and Sandra L. Rodriguez-Zas and Jonathan V. Sweedler},
  journal={Peptides},
  year={2006},
  volume={27 5},
  pages={1087-98}
}
Genomic information is becoming available for an ever-wider range of animals with the genes for several well-characterized peptide families, such as the RFamides, detected in a surprisingly diverse set of these animals. While bioinformatic tools allow the prediction of the RFamide-related prohormones from genetic information, it is more difficult to accurately predict the final processed peptides because of the large number of processing steps required to convert a prohormone into mature… CONTINUE READING