Prediction of intracellular metabolic states from extracellular metabolomic data

@inproceedings{Aurich2014PredictionOI,
  title={Prediction of intracellular metabolic states from extracellular metabolomic data},
  author={Maike K. Aurich and Giuseppe Paglia and {\'O}ttar Rolfsson and Sigr{\'u}n Hrafnsd{\'o}ttir and Manuela Magn{\'u}sd{\'o}ttir and Magdalena M. Stefaniak and Bernhard O. Palsson and Ronan M. T. Fleming and Ines Thiele},
  booktitle={Metabolomics},
  year={2014}
}
Metabolic models can provide a mechanistic framework to analyze information-rich omics data sets, and are increasingly being used to investigate metabolic alternations in human diseases. An expression of the altered metabolic pathway utilization is the selection of metabolites consumed and released by cells. However, methods for the inference of intracellular metabolic states from extracellular measurements in the context of metabolic models remain underdeveloped compared to methods for other… CONTINUE READING

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