Prediction of high risk Ewing's sarcoma by gene expression profiling

@article{Ohali2004PredictionOH,
  title={Prediction of high risk Ewing's sarcoma by gene expression profiling},
  author={Anat Ohali and Smadar Avigad and Rina Zaizov and Ron Ophir and Shirley Horn-Saban and Ian Joseph Cohen and Isaac Meller and Yehuda Kollender and Josephine Issakov and Isaac Yaniv},
  journal={Oncogene},
  year={2004},
  volume={23},
  pages={8997-9006}
}
Ewing's sarcoma (ES) is the second most common primary malignant bone tumor in children and adolescents. Currently accepted clinical prognostic factors fail to classify ES patients' risk to relapse at diagnosis. We aimed to find a new strategy to distinguish between poor and good prognosis ES patients already at diagnosis. We analysed the gene expression profiles of 14 primary tumor specimens and six metastases from ES patients, using oligonucleotide microarray analysis. The over-expression of… CONTINUE READING

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