Prediction of gestational diabetes mellitus in a high-risk group by insulin measurement in early pregnancy.

@article{Bito2005PredictionOG,
  title={Prediction of gestational diabetes mellitus in a high-risk group by insulin measurement in early pregnancy.},
  author={T. Bito and Imre F{\"o}ldesi and Tibor Ny{\'a}ri and Attila P{\'a}l},
  journal={Diabetic medicine : a journal of the British Diabetic Association},
  year={2005},
  volume={22 10},
  pages={1434-9}
}
AIMS We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman, and can serve as a predictor of gestational diabetes mellitus (GDM). METHODS A 2-h, 75-g oral glucose tolerance test (OGTT), with fasting and 2-h postprandial serum insulin determination, was performed in 71 pregnant women with one or more risk factors for GDM before gestation week 16. In 64 patients, subsequent OGTTs were performed at… CONTINUE READING

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We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman , and can serve as a predictor of gestational diabetes mellitus ( GDM ) . METHODS .
We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman , and can serve as a predictor of gestational diabetes mellitus ( GDM ) . METHODS .
We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman , and can serve as a predictor of gestational diabetes mellitus ( GDM ) . METHODS .
We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman , and can serve as a predictor of gestational diabetes mellitus ( GDM ) . METHODS .
We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman , and can serve as a predictor of gestational diabetes mellitus ( GDM ) . METHODS .
We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman , and can serve as a predictor of gestational diabetes mellitus ( GDM ) . METHODS .
We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman , and can serve as a predictor of gestational diabetes mellitus ( GDM ) . METHODS .
Increased serum insulin levels both at fasting and 120 min before gestation week 16 were very strong predictive factors for GDM by gestation weeks 32 - 34 with an odds ratio of 16.6 and 13.3 , respectively .
Insulin determination at fasting and at 120 min had sensitivities of 69.2% and 92.3% , and specificities of 96.4% and 85.7% , respectively , for the prediction of GDM at gestation weeks 24 - 28 .
The sensitivities decreased to 33.3% and 75.0% , respectively , for the prediction of GDM at gestation weeks 32 - 34 .
Insulin determination at fasting and at 120 min had positive predictive values of 0.90 and 0.75 , respectively , for the prediction of GDM at gestation weeks 32 - 34 .
Increased serum insulin levels both at fasting and 120 min before gestation week 16 were very strong predictive factors for GDM by gestation weeks 32 - 34 with an odds ratio of 16.6 and 13.3 , respectively .
Insulin determination at fasting and at 120 min had sensitivities of 69.2% and 92.3% , and specificities of 96.4% and 85.7% , respectively , for the prediction of GDM at gestation weeks 24 - 28 .
The sensitivities decreased to 33.3% and 75.0% , respectively , for the prediction of GDM at gestation weeks 32 - 34 .
Insulin determination at fasting and at 120 min had positive predictive values of 0.90 and 0.75 , respectively , for the prediction of GDM at gestation weeks 32 - 34 .
Insulin determination at fasting and at 120 min had positive predictive values of 0.90 and 0.75 , respectively , for the prediction of GDM at gestation weeks 32 - 34 .
Insulin determination at fasting and at 120 min had sensitivities of 69.2% and 92.3% , and specificities of 96.4% and 85.7% , respectively , for the prediction of GDM at gestation weeks 24 - 28 .
Increased serum insulin levels both at fasting and 120 min before gestation week 16 were very strong predictive factors for GDM by gestation weeks 32 - 34 with an odds ratio of 16.6 and 13.3 , respectively .
The sensitivities decreased to 33.3% and 75.0% , respectively , for the prediction of GDM at gestation weeks 32 - 34 .
We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman , and can serve as a predictor of gestational diabetes mellitus ( GDM ) . METHODS .
We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman , and can serve as a predictor of gestational diabetes mellitus ( GDM ) . METHODS .
We hypothesized that an increased serum insulin level in early pregancy reflects an increased demand on the compensatory capacity of the pregnant woman , and can serve as a predictor of gestational diabetes mellitus ( GDM ) . METHODS .
Insulin determination at fasting and at 120 min had positive predictive values of 0.90 and 0.75 , respectively , for the prediction of GDM at gestation weeks 32 - 34 .
Insulin determination at fasting and at 120 min had sensitivities of 69.2% and 92.3% , and specificities of 96.4% and 85.7% , respectively , for the prediction of GDM at gestation weeks 24 - 28 .
Increased serum insulin levels both at fasting and 120 min before gestation week 16 were very strong predictive factors for GDM by gestation weeks 32 - 34 with an odds ratio of 16.6 and 13.3 , respectively .
The sensitivities decreased to 33.3% and 75.0% , respectively , for the prediction of GDM at gestation weeks 32 - 34 .
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