Prediction of equibiaxial loading stress in collagen-based extracellular matrix using a three-dimensional unit cell model.

Abstract

Mechanical signals are important factors in determining cell fate. Therefore, insights as to how mechanical signals are transferred between the cell and its surrounding three-dimensional collagen fibril network will provide a basis for designing the optimum extracellular matrix (ECM) microenvironment for tissue regeneration. Previously we described a… (More)
DOI: 10.1016/j.actbio.2012.10.028

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