Prediction of early, intermediate and late pre‐eclampsia from maternal factors, biophysical and biochemical markers at 11–13 weeks

@article{Akolekar2011PredictionOE,
  title={Prediction of early, intermediate and late pre‐eclampsia from maternal factors, biophysical and biochemical markers at 11–13 weeks},
  author={Ranjit Akolekar and Argyro Syngelaki and Rita Sarquis and Mona Elena Zv{\^a}ncă and Kypros H. Nicolaides},
  journal={Prenatal Diagnosis},
  year={2011},
  volume={31}
}
To develop models for prediction of pre‐eclampsia (PE) based on maternal factors and biophysical and biochemical markers at 11–13 weeks' gestation. 
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Prediction of early and late pre‐eclampsia from maternal characteristics, uterine artery Doppler and markers of vasculogenesis during first trimester of pregnancy
  • M. Parra‐Cordero, R. Rodrigo, +4 authors S. Quezada
  • Medicine
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • 2013
TLDR
A predictive model is developed for pre‐eclampsia using clinical, biochemical and ultrasound markers during the first trimester of pregnancy to develop a predictive model for pre-ecl hypertension.
Screening for pre‐eclampsia early in pregnancy: performance of a multivariable model combining clinical characteristics and biochemical markers
To investigate the performance of a multivariable model combining a priori clinical characteristics and biomarkers to detect, early in pregnancy, women at higher risk of developing pre‐eclampsia (PE).
Screening for pre‐eclampsia by maternal factors and biomarkers at 11–13 weeks' gestation
  • M. Tan, A. Syngelaki, +17 authors K. Nicolaides
  • Medicine
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • 2018
To examine the performance of screening for early, preterm and term pre‐eclampsia (PE) at 11–13 weeks' gestation by maternal factors and combinations of mean arterial pressure (MAP), uterine artery…
First‐ and second‐trimester maternal serum markers of pre‐eclampsia in twin pregnancy
TLDR
To evaluate the distribution of first‐ and second‐trimester maternal serum markers in twin pregnancy with and without pre‐eclampsia, a large number of samples were collected from women in the first and second trimester of pregnancy.
First trimester screening for early and late preeclampsia based on maternal characteristics, biophysical parameters, and angiogenic factors
The aim of this article is to develop the best first‐trimester screening model for preeclampsia (PE) based on maternal characteristics, biophysical parameters, and angiogenic factors in a low‐risk…
Angiogenic factors combined with clinical risk factors to predict preterm pre‐eclampsia in nulliparous women: a predictive test accuracy study
To assess the performance of clinical risk factors, uterine artery Doppler and angiogenic markers to predict preterm pre‐eclampsia in nulliparous women.
First‐trimester prediction of pre‐eclampsia: external validity of algorithms in a prospectively enrolled cohort
TLDR
To evaluate the performance of published first‐trimester prediction algorithms for pre‐eclampsia (PE) in a prospectively enrolled cohort of women, a large number of women were enrolled for the first trimester of their second trimester.
Economic assessment of screening for pre‐eclampsia
TLDR
Routine screening for pre‐eclampsia using placental markers and placental growth factor and uterine artery Doppler compared with standard care is assessed to economically assess.
External validity of first‐trimester algorithms in the prediction of pre‐eclampsia disease severity
To compare disease features in women with pre‐eclampsia between those who are correctly identified (true positive) and those who are missed (false negative) when applying first‐trimester prediction…
First‐trimester maternal ophthalmic artery Doppler analysis for prediction of pre‐eclampsia
To determine the performance of a multiparametric test comprising maternal risk factors, uterine artery Doppler and ophthalmic artery Doppler in the first trimester of pregnancy for the prediction of…
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References

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TLDR
To investigate the potential value of maternal serum placental growth factor (PlGF) in first‐trimester screening for pre‐eclampsia (PE) and its role in pregnancy development, a large number of women were enrolled for screening.
Uterine artery Doppler at 11 + 0 to 13 + 6 weeks in the prediction of pre‐eclampsia
TLDR
To determine the performance of screening for pre‐eclampsia (PET) by maternal characteristics and uterine artery pulsatility index (PI) at 11 + 0 to 13 + 6 weeks' gestation, a large number of women with high‐risk pregnancies are surveyed.
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To examine the performance of screening for pre‐eclampsia (PE) by a combination of maternal factors, soluble endoglin (sEng), pregnancy associated plasma protein‐A (PAPP‐A), placental growth factor…
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To examine the relationship between low maternal serum pregnancy‐associated plasma protein‐A (PAPP‐A) and uterine artery pulsatility index (UtA‐PI) at 11 + 0 to 13 + 6 weeks with subsequent…
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To develop a model for the prediction of gestational diabetes mellitus (GDM) from maternal characteristics and biochemical markers at 11 to 13 weeks' gestation.
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TLDR
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Prediction of spontaneous preterm delivery from maternal factors, obstetric history and placental perfusion and function at 11–13 weeks
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TLDR
To investigate the potential value of maternal plasma inhibin A in first‐trimester screening for preeclampsia, a small number of women were randomly assigned to receive a low or high dose of the drug.
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TLDR
To examine the potential value of maternal serum concentration of placental protein 13 at 11–13 weeks' gestation in screening for preeclampsia (PE), a serum concentration study is performed on women during pregnancy.
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