Prediction of drug target groups based on chemical-chemical similarities and chemical-chemical/protein connections.


Drug-target interaction is a key research topic in drug discovery since correct identification of target proteins of drug candidates can help screen out those with unacceptable toxicities, thereby saving expense. In this study, we developed a novel computational approach to predict drug target groups that may reduce the number of candidate target proteins… (More)
DOI: 10.1016/j.bbapap.2013.05.021