Prediction of drug-drug interaction potential using physiologically based pharmacokinetic modeling.

@article{Min2017PredictionOD,
  title={Prediction of drug-drug interaction potential using physiologically based pharmacokinetic modeling.},
  author={Jee Sun Min and Soo Hyeon Bae},
  journal={Archives of pharmacal research},
  year={2017},
  volume={40 12},
  pages={
          1356-1379
        }
}
The occurrence of drug-drug interactions (DDIs) can significantly affect the safety of a patient, and thus assessing DDI risk is important. Recently, physiologically based pharmacokinetic (PBPK) modeling has been increasingly used to predict DDI potential. Here, we present a PBPK modeling concept and strategy. We also surveyed PBPK-related articles about… CONTINUE READING