Prediction of dinucleotide-specific RNA-binding sites in proteins

  title={Prediction of dinucleotide-specific RNA-binding sites in proteins},
  author={Michael Fern{\'a}ndez and Yutaro Kumagai and Daron M. Standley and Akinori Sarai and Kenji Mizuguchi and Shandar Ahmad},
  booktitle={BMC Bioinformatics},
Regulation of gene expression, protein synthesis, replication and assembly of many viruses involve RNA–protein interactions. Although some successful computational tools have been reported to recognize RNA binding sites in proteins, the problem of specificity remains poorly investigated. After the nucleotide base composition, the dinucleotide is the smallest unit of RNA sequence information and many RNA-binding proteins simply bind to regions enriched in one dinucleotide. Interaction… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 16 extracted citations


Publications referenced by this paper.
Showing 1-10 of 34 references

Prediction of protein-RNA binding sites by a random forest method with combined features

  • Liu Z-P, Wu L-Y, Y Wang, Zhang X-S, L Chen
  • Bioinformatics (Oxford,
  • 2010
1 Excerpt

Similar Papers

Loading similar papers…