Prediction of conserved microRNAs from skin and mucosal human papillomaviruses

  title={Prediction of conserved microRNAs from skin and mucosal human papillomaviruses},
  author={Wenyi Gu and Jiyuan An and Ping Ye and Kong-nan Zhao and Annika Antonsson},
  journal={Archives of Virology},
Eight human papillomavirus (HPV) types including four cutaneous HPV types (HPV-5, HPV-8, HPV-20 and HPV-38) and four mucosal HPV types (HPV-6, HPV-11, HPV-16 and HPV-18) were selected for this miRNA study. Pre-miRNAs were predicted using a computer programme, and the conserved mature miRNAs were compared to currently known miRNAs. Predicted HPV miRNAs related to miR-466, -467 and -669 were common and specific to the mucosal HPV types. Northern blot hybridization confirmed a predicted miRNA in… CONTINUE READING
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