Prediction of conserved long-range RNA-RNA interactions in full viral genomes

@article{Fricke2016PredictionOC,
  title={Prediction of conserved long-range RNA-RNA interactions in full viral genomes},
  author={Markus Fricke and Manja Marz},
  journal={Bioinformatics},
  year={2016},
  volume={32 19},
  pages={2928-35}
}
MOTIVATION Long-range RNA-RNA interactions (LRIs) play an important role in viral replication, however, only a few of these interactions are known and only for a small number of viral species. Up to now, it has been impossible to screen a full viral genome for LRIs experimentally or in silico Most known LRIs are cross-reacting structures (pseudoknots) undetectable by most bioinformatical tools. RESULTS We present LRIscan, a tool for the LRI prediction in full viral genomes based on a multiple… CONTINUE READING
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