Prediction of cognitive decline by positron emission tomography of brain amyloid and tau.

Abstract

OBJECTIVE To determine whether 2-(1-{6-[(2-fluorine 18-labeled fluoroethyl)methylamino]-2-napthyl}ethylidene) malononitrile ([(18)F]FDDNP) brain regional values in individuals without dementia predict and correlate with future cognitive change. DESIGN Two-year, longitudinal follow-up study. SETTING A university research institute. PARTICIPANTS… (More)
DOI: 10.1001/archneurol.2011.559

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