Prediction of clinical severity and outcome of ventilator-associated pneumonia. Comparison of simplified acute physiology score with systemic inflammatory mediators.

@article{Froon1998PredictionOC,
  title={Prediction of clinical severity and outcome of ventilator-associated pneumonia. Comparison of simplified acute physiology score with systemic inflammatory mediators.},
  author={A H Froon and Marc J. M. Bonten and Carlo Ajm Gaillard and Jan Willem M. Greve and Mieke A. Dentener and Peter Wilhelmus de Leeuw and Marjolein Drent and Ellen E. Stobberingh and Wim A. Buurman},
  journal={American journal of respiratory and critical care medicine},
  year={1998},
  volume={158 4},
  pages={
          1026-31
        }
}
Systemic kinetics of three inflammatory mediators (bactericidal/permeability-increasing protein [BPI], soluble intercellular adhesion molecule [sICAM], and soluble E-selectin [sE-selectin]) were studied during the development of ventilator-associated pneumonia (VAP) (n = 42), diagnosed on quantitative cultures of bronchoscopic samples. From a pool of collected samples, nested samples were used to measure mediators on Days -4, -2, 0, and +2, relative to diagnosis. Correlations between systemic… CONTINUE READING

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