Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis.

@article{Lorenz2007PredictionOC,
  title={Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis.},
  author={Matthias W. Lorenz and Hugh S. Markus and Michiel L. Bots and Maria Rosvall and Matthias Sitzer},
  journal={Circulation},
  year={2007},
  volume={115 4},
  pages={459-67}
}
BACKGROUND Carotid intima-media thickness (IMT) is increasingly used as a surrogate marker for atherosclerosis. Its use relies on its ability to predict future clinical cardiovascular end points. We performed a systematic review and meta-analysis of data to examine this association. METHODS AND RESULTS Using a prespecified search strategy, we identified 8 relevant studies and compared study design, measurement protocols, and reported data. We identified sources of heterogeneity between… CONTINUE READING
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