Prediction of bone density around orthopedic implants delivering bisphosphonate.

@article{Stadelmann2009PredictionOB,
  title={Prediction of bone density around orthopedic implants delivering bisphosphonate.},
  author={Vincent A Stadelmann and Alexandre Terrier and Olivier Gauthier and J-M Bouler and Dominique P. Pioletti},
  journal={Journal of biomechanics},
  year={2009},
  volume={42 9},
  pages={
          1206-11
        }
}
The fixation of an orthopedic implant depends strongly upon its initial stability. Peri-implant bone may resorb shortly after the surgery. This resorption is directly followed by new bone formation and implants fixation strengthening, the so-called secondary fixation. If the initial stability is not reached, the resorption continues and the implant fixation weakens, which leads to implant loosening. Studies with rats and dogs have shown that a solution to prevent peri-implant resorption is to… CONTINUE READING

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