Prediction of accumulation of 131I-labelled meta-iodobenzylguanidine in neuroblastoma cell lines by means of reverse transcription and polymerase chain reaction.

@article{Mairs1994PredictionOA,
  title={Prediction of accumulation of 131I-labelled meta-iodobenzylguanidine in neuroblastoma cell lines by means of reverse transcription and polymerase chain reaction.},
  author={Robert J. Mairs and Anne Livingstone and Mark Nicholas Gaze and T. E. Wheldon and Ann Barrett},
  journal={British Journal of Cancer},
  year={1994},
  volume={70},
  pages={97 - 101}
}
Radiolabelled meta-iodobenzylguanidine (mIBG) currently provides one of the most promising options for targeted radiotherapy of neuroblastoma. No means currently exists for prediction of mIBG uptake in tumour cells of individual patients other than semiquantitative inferences from diagnostic scanning which depend on the continued existence of a macroscopic tumour mass. A biological rapid assay which could be applied at initial biopsy would be invaluable in selecting patients for therapeutic… CONTINUE READING

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