Prediction of Toxicant-Specific Gene Expression Signatures after Chemotherapeutic Treatment of Breast Cell Lines

Abstract

Global gene expression profiling has demonstrated that the predominant cellular response to a range of toxicants is a general stress response. This stereotyped environmental stress response commonly includes repression of protein synthesis and cell-cycle-regulated genes and induction of DNA damage and oxidative stress-responsive genes. Our laboratory… (More)

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@inproceedings{Troester2004PredictionOT, title={Prediction of Toxicant-Specific Gene Expression Signatures after Chemotherapeutic Treatment of Breast Cell Lines}, author={Melissa A. Troester and Katherine A Hoadley and Joel S. Parker and Charles M. Perou}, booktitle={Environmental health perspectives}, year={2004} }