Prediction of Protein Folds: Extraction of New Features, Dimensionality Reduction, and Fusion of Heterogeneous Classifiers

@article{Ghanty2009PredictionOP,
  title={Prediction of Protein Folds: Extraction of New Features, Dimensionality Reduction, and Fusion of Heterogeneous Classifiers},
  author={Pradip Ghanty and N. R. Pal},
  journal={IEEE Transactions on NanoBioscience},
  year={2009},
  volume={8},
  pages={100-110}
}
Here, we consider a two-level (four classes in level 1 and 27 folds in level 2) protein fold determination problem. We propose several new features and use some existing features including frequencies of adjacent residues, frequencies of residues separated by one residue, and triplets (trio) of amino acid compositions (AACs). The dimensionality of the trio… CONTINUE READING