Prediction of Neurological Enzyme Targets for Known and New Compounds with a Model using Galvez ' s Topological Indices

@inproceedings{PradoPrado2014PredictionON,
  title={Prediction of Neurological Enzyme Targets for Known and New Compounds with a Model using Galvez ' s Topological Indices},
  author={Francisco J. Prado-Prado and Humberto Gonz{\'a}lez-D{\'i}az and Eduardo Sobarzo-S{\'a}nchez and Isela Garc{\'i}a-Pintos},
  year={2014}
}
Alzheimer's Disease (AD), Parkinson, and other neurodegenerative diseases are a major health problem nowadays. However, in many cases, current therapies are merely palliative and only temporarily slow cognitive decline. In this sense, the discovery of new drugs for the treatment of neurodegenerative diseases is a goal of the major importance. Public databases, like ChEMBL, contain a large amount of data about multiplexing assays of inhibitors of a group of enzymes with special relevance in… CONTINUE READING