Prediction of MHC Class II Binding Peptides Using a Multi-Objective Evolutionary Algorithm

Abstract

The identification of T-cell epitopes is important for vaccine development. An epitope is a peptide segment that can bind to both a T-cell receptor and a major histocompatibility complex (MHC) molecule. The prediction of MHC binding peptides is a crucial part of the epitopes identification. This paper presents a novel Multi-Objective Evolutionary Algorithm… (More)
DOI: 10.1109/CIS.2007.180

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