Prediction of Escherichia coli expression performance in microtiter plates by analyzing only the temporal development of scattered light during culture


BACKGROUND Escherichia coli is often used for recombinant protein production. The expression of recombinant proteins negatively affects the microbial growth, thus, a balance between protein expression and biomass formation is preferable to reach high product- and space-time-yield. Already in screening experiments, suboptimal conditions causing too weak or… (More)
DOI: 10.1186/s13036-017-0064-5


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