Prediction of Early Childhood Caries via Spatial-Temporal Variations of Oral Microbiota.

@article{Teng2015PredictionOE,
  title={Prediction of Early Childhood Caries via Spatial-Temporal Variations of Oral Microbiota.},
  author={Fei Teng and Fang Yang and Shi Huang and Cunpei Bo and Zhenjiang Zech Xu and Amnon Amir and Rob Knight and Junqi Ling and Jian Xu},
  journal={Cell host & microbe},
  year={2015},
  volume={18 3},
  pages={296-306}
}
Microbiota-based prediction of chronic infections is promising yet not well established. Early childhood caries (ECC) is the most common infection in children. Here we simultaneously tracked microbiota development at plaque and saliva in 50 4-year-old preschoolers for 2 years; children either stayed healthy, transitioned into cariogenesis, or experienced caries exacerbation. Caries onset delayed microbiota development, which is otherwise correlated with aging in healthy children. Both plaque… CONTINUE READING
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