Prediction of Disordered Regions and Their Roles in the Anti-Pathogenic and Immunomodulatory Functions of Butyrophilins

  title={Prediction of Disordered Regions and Their Roles in the Anti-Pathogenic and Immunomodulatory Functions of Butyrophilins},
  author={Elrashdy M. Redwan and Ahmed M. Al-Hejin and Hussein A. Almehdar and Abdelrahman M Elsaway and Vladimir N. Uversky},
  journal={Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry},
  • E. Redwan, A. Al-Hejin, V. Uversky
  • Published 1 February 2018
  • Biology
  • Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Butyrophilins (BTNs) are a group of the moonlighting proteins, some members of which are secreted in milk. They constitute a large family of structurally similar type 1 transmembrane proteins from the immunoglobulin superfamily. Although the founding member of this family is related to lactation, participating in the secretion, formation and stabilization of milk fat globules, it may also have a cell surface receptor function. Generally, the BTN family members are known to modulate co… 
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