Prediction of Associations between microRNAs and Gene Expression in Glioma Biology

Abstract

Despite progress in the determination of miR interactions, their regulatory role in cancer is only beginning to be unraveled. Utilizing gene expression data from 27 glioblastoma samples we found that the mere knowledge of physical interactions between specific mRNAs and miRs can be used to determine associated regulatory interactions, allowing us to… (More)
DOI: 10.1371/journal.pone.0014681

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