Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides.

@article{Hglund2008PredictionOA,
  title={Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides.},
  author={Kina H{\"o}glund and Oskar Hansson and Peder Buchhave and Henrik Zetterberg and Piotr Lewczuk and Elisabet Y Londos and K Blennow and Lennart Minthon and Jens Wiltfang},
  journal={Neuro-degenerative diseases},
  year={2008},
  volume={5 5},
  pages={268-76}
}
BACKGROUND Identifying individuals at high risk of developing Alzheimer's disease (AD) is important for future therapeutic strategies, and there is a clinical need for diagnostic biomarkers to identify incipient AD. OBJECTIVE The aim of the present study was to investigate if the AD-associated Abeta peptide pattern recently found in cerebrospinal fluid (CSF) could discriminate between patients with incipient AD and those with stable mild cognitive impairment (MCI) by analyzing CSF from… CONTINUE READING

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