Prediction of ART Outcome in Male Factor Infertility Patients by a New Semen Quality Score

  title={Prediction of ART Outcome in Male Factor Infertility Patients by a New Semen Quality Score},
  author={Ashok Agarwal and Rakesh Sharma},
INTRODUCTION Semen analysis is arguably the most important clinical laboratory test available in the evaluation of male infertility. Measures of semen quality are used as surrogate measures of male fecundity in clinical andrology, reproductive toxicology, epidemiology, and risk assessment. However, the implications of even moderate alterations in semen quality are poorly understood, and only limited data are available for relating these measures to the likelihood of achieving pregnancy. In… Expand


The impact of sperm morphology evaluated by strict criteria on intrauterine insemination success.
Intrauterine insemination appears to be a successful treatment modality for male factor infertility, even when the percentage of morphologically normal sperm in raw semen is very low. Expand
Advanced semen analysis: a simple screening test to predict intrauterine insemination success.
The number of motile sperm available for insemination and especially their 24-hour survival are highly predictive of IUI success and this advanced semen analysis is an excellent screening test to evaluate couples considering IUI. Expand
Computer-assisted semen analysis parameters as predictors for fertility of men from the general population. The Danish First Pregnancy Planner Study Team.
The predictive value of sperm motility parameters obtained by computer-assisted semen analysis (CASA) was evaluated for the fertility of men from general population. In a prospective study withExpand
Sperm function assays and their predictive value for fertilization outcome in IVF therapy: a meta-analysis.
An objective, outcome-based examination of the validity of the currently available assays demonstrated a high predictive power of the sperm-zona pellucida binding and the induced-acrosome reaction assays for fertilization outcome, but indicated a poor clinical value of the SPA as predictor of fertilization. Expand
Comparison of the sperm quality necessary for successful intrauterine insemination with World Health Organization threshold values for normal sperm.
The sperm quality that is necessary for successful IUI is lower than World Health Organization threshold values for normal sperm, and intrauterine insemination is effective therapy for male factor infertility when initial sperm motility is < or = 30% and the total motile sperm count is > or = 5 X 10(6). Expand
Semen parameters in a fertile versus subfertile population: a need for change in the interpretation of semen testing
This prospectively designed study was conducted to compare a fertile and a subfertile population so as to define normal values for different semen parameters. Semen analyses were performed accordingExpand
Spermatozoal characteristics from fresh and frozen donor semen and their correlation with fertility outcome after intrauterine insemination.
The hypothesis that the study of sperm motion characteristics using CASA after thawing and washing of cryopreserved sperm is a better predictor of fertile outcome after IUI than analysis of fresh semen is supported. Expand
Effect of the total motile sperm count on the efficacy and cost-effectiveness of intrauterine insemination and in vitro fertilization.
An average total motile sperm count of 10 million may be a useful threshold value for decisions about treating a couple with IUI or IVF, and only female age was an important predictor for both clinical and ongoing pregnancy. Expand
Sperm morphology analysis (strict criteria) in male infertility is not a prognostic factor in intrauterine insemination with husband's sperm.
Strict morphology analysis 1 month before the beginning of IUI is not a useful prognostic factor in IUI performed because of male infertility. Expand
The predictive value of computer-assisted semen analysis in the context of a donor insemination programme.
It was concluded that CASA assessment is of significant value in predicting the ability of an ejaculate to achieve pregnancy. Expand