Prediction and preliminary validation of oncogene regulation by miRNAs

@article{Koscianska2007PredictionAP,
  title={Prediction and preliminary validation of oncogene regulation by miRNAs},
  author={Edyta Koscianska and Vesselin Baev and Konstantinia Skreka and Katerina Oikonomaki and Ventsislav Rusinov and Martin Tabler and Kriton Kalantidis},
  journal={BMC Molecular Biology},
  year={2007},
  volume={8},
  pages={79 - 79}
}
BackgroundMicroRNAs (miRNAs) are one of the most abundant groups of regulatory genes in multicellular organisms, playing important roles in many fundamental cellular processes. More than four hundred miRNAs have been identified in humans and the deregulation of miRNA expression has been also shown in many cancers. Despite the postulated involvement of miRNAs in tumourigenesis, there are only a few examples where an oncogene or a tumour suppressor has been identified as a miRNA target… CONTINUE READING
BETA

Tables and Topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
SHOWING 1-10 OF 34 CITATIONS

The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice

  • Journal of Cancer Research and Clinical Oncology
  • 2009
VIEW 6 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Downregulated microRNA-510-5p acts as a tumor suppressor in renal cell carcinoma.

  • Molecular medicine reports
  • 2015
VIEW 1 EXCERPT
CITES BACKGROUND

Role of Exosomal Noncoding RNAs in Lung Carcinogenesis

  • BioMed research international
  • 2015
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 99 REFERENCES

miR-15 and miR-16 induce apoptosis by targeting BCL2.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2005
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

A microRNA expression signature of human solid tumors defines cancer gene targets.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2006
VIEW 2 EXCERPTS

Similar Papers

Loading similar papers…