Predicting the outcome of severe ulcerative colitis: development of a novel risk score to aid early selection of patients for second-line medical therapy or surgery.

@article{Ho2004PredictingTO,
  title={Predicting the outcome of severe ulcerative colitis: development of a novel risk score to aid early selection of patients for second-line medical therapy or surgery.},
  author={Gwo-Tzer Ho and Craig Mowat and Charlotte Goddard and John F. Fennell and Neel B. Shah and Robin J. Prescott and Jack Satsangi},
  journal={Alimentary pharmacology & therapeutics},
  year={2004},
  volume={19 10},
  pages={1079-87}
}
BACKGROUND The failure rate of medical therapy in severe ulcerative colitis is high. A risk index, to aid the identification of patients of not responding at an early stage to intravenous corticosteroid therapy, would be useful to facilitate second-line treatment or surgery. METHODS We recruited 167 consecutive patients with severe ulcerative colitis between January 1995 and March 2002; and employed multiple logistic regression to analyse parameters within the first 3 days of medical therapy… CONTINUE READING